Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4298262 | 0.86 | ALDH1A1 (0.45) | KMT2AMEN1ABHD6HTTALDH1A1 | |
| SCHEMBL4752523 | 0.85 | ABHD6 (0.43) | KMT2AMEN1ABHD6HTTALDH1A1 | |
| SCHEMBL4297012 | 0.81 | MEN1 (0.46) | KMT2AMEN1HTTALDH1A1KDM4E | |
| SCHEMBL4303757 | 0.80 | ABHD6 (0.41) | KMT2AMEN1ABHD6HTTALDH1A1 | |
| SCHEMBL4296960 | 0.80 | L3MBTL1 (0.47) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL4301342 | 0.78 | ALDH1A1 (0.42) | KMT2AMEN1ABHD6ALDH1A1KDM4E | |
| SCHEMBL4293508 | 0.78 | ALDH1A1 (0.42) | KMT2AMEN1ABHD6ALDH1A1KDM4E | |
| SCHEMBL4753584 | 0.78 | ALDH1A1 (0.46) | KMT2AABHD6HTTALDH1A1MAPT | |
| SCHEMBL4752095 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KDM4EPOLBGAALMNA | |
| SCHEMBL4750109 | 0.77 | ALDH1A1 (0.40) | KMT2AMEN1ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |