Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753250 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4756577 | 0.81 | MAPT (0.47) | DHFRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4756506 | 0.77 | DHFR (0.50) | DHFRMEN1KMT2A | |
| SCHEMBL4755431 | 0.76 | HTT (0.44) | — | |
| SCHEMBL4753175 | 0.76 | DHFR (0.46) | DHFR | |
| SCHEMBL4755522 | 0.76 | KMT2A (0.46) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4753631 | 0.76 | KMT2A (0.43) | DHFRMAPTMEN1KMT2A | |
| SCHEMBL4755444 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MAPT | |
| SCHEMBL13984040 | 0.75 | DHFR (0.53) | DHFRALDH1A1MAPT | |
| SCHEMBL4755224 | 0.75 | DHFR (0.52) | DHFRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | claimed |
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008152142-A1 | 2 -AMINOQUINAZOLINE DERIVATIVES AND THEIR THERAPEUTIC USES | SOFTCURE PHARMACEUTICALS AB (SE) | 2008-12-18 | — | — | WO | disclosed |