Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4164714 | 0.92 | ALDH1A1 (0.37) | MEN1KMT2ALIPGLPLCYP1A2 | |
| SCHEMBL1689355 | 0.76 | DHFR (0.41) | MEN1KMT2ACYP1A2USP2CASP1 | |
| SCHEMBL4172454 | 0.76 | LPL (0.40) | MEN1KMT2ALIPGLPLCYP1A2 | |
| SCHEMBL2116610 | 0.75 | DHFR (0.43) | MEN1KMT2ACYP1A2USP2CASP1 | |
| SCHEMBL4786879 | 0.74 | MAPT (0.41) | MEN1KMT2ALIPGLPLCYP1A2 | |
| SCHEMBL4166791 | 0.72 | USP2 (0.41) | MEN1KMT2ACYP1A2USP2CASP1 | |
| SCHEMBL1753378 | 0.72 | AKR1B10 (0.42) | MEN1KMT2ALMNAALOX15KDM4E | |
| SCHEMBL1753132 | 0.71 | MAPT (0.40) | MEN1KMT2ALIPGLPLCYP1A2 | |
| SCHEMBL1689195 | 0.70 | DHFR (0.42) | MEN1KMT2ALMNAKDM4EMAPT | |
| SCHEMBL1753381 | 0.70 | MAPT (0.65) | KMT2AALDH1A1LMNAALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999132-A1 | AZOLOPYRIMIDINES AS INHIBITORS OF CANNABINOID 1 ACTIVITY | IRM, LLC (BM) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007120454-A1 | AZOLOPYRIMIDINES AS INHIBITORS OF CANNABINOID 1 ACTIVITY | IRM LLC (BM) | 2007-10-25 | — | — | WO | disclosed |