Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753787 | 1.00 | POLB (0.36) | POLBKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL4755477 | 0.71 | HSD11B1 (0.39) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL4755474 | 0.71 | HSD11B1 (0.39) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL4755475 | 0.71 | HSD11B1 (0.39) | KMT2AMEN1ALDH1A1HPGDMAPT | |
| SCHEMBL4756989 | 0.70 | POLB (0.33) | POLBKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL4756985 | 0.70 | POLB (0.33) | POLBKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL4756083 | 0.68 | MEN1 (0.33) | POLBKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL10073907 | 0.67 | CTSC (0.43) | MAPTOTUD7BKDM4ELMNAHIF1A | |
| SCHEMBL7689385 | 0.60 | ALDH1A1 (0.47) | ALDH1A1TSHRTACR1 | |
| SCHEMBL11574706 | 0.59 | ALDH1A1 (0.40) | KMT2AMEN1ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008155619-A2 | PREPARATION OF OPTICALLY-ACTIVE CYCLIC AMINO ACIDS | PFIZER INC. (US) | 2008-12-24 | — | — | WO | disclosed |