Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10916647 | 0.86 | MEN1 (0.41) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL5147546 | 0.82 | ALDH1A1 (0.41) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL140993 | 0.81 | KMT2A (0.43) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL10486326 | 0.80 | ALDH1A1 (0.39) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL4990027 | 0.80 | CYP1A2 (0.40) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL9765834 | 0.80 | KMT2A (0.41) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL3912338 | 0.80 | MEN1 (0.37) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL29083223 | 0.79 | MEN1 (0.41) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL11000896 | 0.78 | KMT2A (0.45) | MEN1ESR1KMT2AESR2GAA | |
| SCHEMBL8654494 | 0.78 | KMT2A (0.45) | MEN1ESR1KMT2AESR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008155619-A2 | PREPARATION OF OPTICALLY-ACTIVE CYCLIC AMINO ACIDS | PFIZER INC. (US) | 2008-12-24 | — | — | WO | disclosed |