Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10916647 | 0.82 | MEN1 (0.41) | KMT2AMEN1ESR1ESR2ATM | |
| SCHEMBL5147546 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1ESR1ESR2ATM | |
| SCHEMBL29083223 | 0.81 | MEN1 (0.41) | KMT2AMEN1ESR1ESR2ATM | |
| SCHEMBL582357 | 0.80 | KMT2A (0.44) | KMT2AMEN1ESR1ESR2ATM | |
| SCHEMBL4753846 | 0.80 | MEN1 (0.39) | KMT2AMEN1ESR1ESR2ATM | |
| SCHEMBL10486326 | 0.80 | ALDH1A1 (0.39) | KMT2AMEN1ESR1ESR2ATM | |
| SCHEMBL21114482 | 0.79 | CA12 (0.38) | KMT2AMEN1ESR1ESR2ALDH1A1 | |
| SCHEMBL6916197 | 0.78 | KMT2A (0.41) | KMT2AMEN1ESR1ESR2ATM | |
| SCHEMBL140993 | 0.78 | KMT2A (0.43) | KMT2AMEN1ESR1ESR2ATM | |
| SCHEMBL4990027 | 0.76 | CYP1A2 (0.40) | KMT2AMEN1ESR1ESR2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013863-A | Learning enhancement | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |