Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982217 | 0.86 | LMNA (0.44) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL10916647 | 0.83 | MEN1 (0.41) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL140993 | 0.81 | KMT2A (0.43) | CYP1A2CYP2C9CYP2C19CA1CA2 | |
| SCHEMBL10486326 | 0.80 | ALDH1A1 (0.39) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL4753846 | 0.80 | MEN1 (0.39) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL29083223 | 0.79 | MEN1 (0.41) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL5147546 | 0.79 | ALDH1A1 (0.41) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL11000896 | 0.78 | KMT2A (0.45) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL8654494 | 0.78 | KMT2A (0.45) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL7340045 | 0.78 | KMT2A (0.45) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | C3AR1, C5, C5AR1 | CYP1A2 1513/4885CYP2C9 3080/4885CYP2C19 1449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.