Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903086 | 0.91 | KMT2A (0.40) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL6156140 | 0.88 | CASP1 (0.43) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL8216091 | 0.86 | TK1 (0.46) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL6154454 | 0.85 | POLB (0.41) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL6157266 | 0.84 | ALDH1A1 (0.39) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL10916647 | 0.84 | MEN1 (0.41) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL6982217 | 0.84 | LMNA (0.44) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL6154515 | 0.83 | POLB (0.37) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL11591943 | 0.82 | KMT2A (0.47) | KMT2AMEN1F2HTTCA1 | |
| SCHEMBL4753846 | 0.81 | MEN1 (0.39) | KMT2AMEN1ESR1ESR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12605471-B2 | Cromolyn derivatives and related methods of imaging and treatment | THE GENERAL HOSPITAL CORPORATION (US) | 2026-04-21 | — | — | US | disclosed |
| US-20240058480-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | THE GENERAL HOSPITAL CORPORATION | 2024-02-22 | — | — | US | disclosed |
| US-11801316-B2 | Cromolyn derivatives and related methods of imaging and treatment | THE GENERAL HOSPITAL CORPORATION (US) | 2023-10-31 | — | — | US | disclosed |
| US-11666669-B2 | Cromolyn derivatives and related methods of imaging and treatment | THE GENERAL HOSPITAL CORPORATION (US) | 2023-06-06 | — | — | US | disclosed |
| US-10576171-B2 | Cromolyn derivatives and related methods of imaging and treatment | THE GENERAL HOSPITAL CORPORATION (US) | 2020-03-03 | — | — | US | disclosed |
| EP-3567033-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | The General Hospital Corporation (US) | 2019-11-13 | — | — | EP | disclosed |
| US-20190231910-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | THE GENERAL HOSPITAL CORPORATION | 2019-08-01 | — | — | US | disclosed |
| US-10251961-B2 | Cromolyn derivatives and related methods of imaging and treatment | THE GENERAL HOSPITAL CORPORATION (US) | 2019-04-09 | — | — | US | disclosed |
| EP-2391618-B1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | MASSACHUSETTS GEN HOSPITAL (US) | 2019-04-03 | — | — | EP | disclosed |
| US-10245331-B2 | Cromolyn derivatives and related methods of imaging and treatment | THE GENERAL HOSPITAL CORPORATION (US) | 2019-04-02 | — | — | US | disclosed |
| US-20180193492-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | THE GENERAL HOSPITAL CORPORATION | 2018-07-12 | — | — | US | disclosed |
| US-20180193491-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | THE GENERAL HOSPITAL CORPORATION | 2018-07-12 | — | — | US | disclosed |
| US-20180169277-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | THE GENERAL HOSPITAL CORPORATION | 2018-06-21 | — | — | US | disclosed |
| US-9925282-B2 | Cromolyn derivatives and related methods of imaging and treatment | THE GENERAL HOSPITAL CORPORATION (US) | 2018-03-27 | — | — | US | disclosed |
| US-20160263257-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | THE GENERAL HOSPITAL CORPORATION | 2016-09-15 | — | — | US | disclosed |
| EP-3060205-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | The General Hospital Corporation DBA Massachusetts (US) | 2016-08-31 | — | — | EP | disclosed |
| WO-2015061397-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | THE GENERAL HOSTPITAL CORPORATION (US) | 2015-04-30 | — | — | WO | disclosed |
| US-20140140927-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | THE GENERAL HOSPITAL CORPORATION (US) | 2014-05-22 | — | — | US | disclosed |
| US-8617517-B2 | Cromolyn derivatives and related methods of imaging and treatment | THE GENERAL HOSPITAL CORPORATION (US) | 2013-12-31 | — | — | US | disclosed |
| US-20120058049-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | THE GENERAL HOSPITAL CORPORATION | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10576171-B2 | Cromolyn derivatives and related methods of imaging and treatment | PSEN1, PSEN2, CROCC | KMT2A 3445/4885MEN1 970/4885ESR1 3295/4885 |
| US-12605471-B2 | Cromolyn derivatives and related methods of imaging and treatment | PSEN1, APP, PSEN2 | KMT2A 4576/4885MEN1 2347/4885ESR1 2398/4885 |
| US-11801316-B2 | Cromolyn derivatives and related methods of imaging and treatment | PSEN1, PSEN2, CROCC | KMT2A 3196/4885MEN1 889/4885ESR1 2983/4885 |
| US-20240058480-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | PSEN1, PSEN2, CROCC | KMT2A 3172/4885MEN1 847/4885ESR1 2852/4885 |
| US-10251961-B2 | Cromolyn derivatives and related methods of imaging and treatment | PSEN1, PSEN2, CROCC | KMT2A 3196/4885MEN1 889/4885ESR1 2983/4885 |
| US-20180193491-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | PSEN1, PSEN2, CROCC | KMT2A 3196/4885MEN1 889/4885ESR1 2983/4885 |
| US-20190231910-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | PSEN1, PSEN2, CROCC | KMT2A 3445/4885MEN1 970/4885ESR1 3295/4885 |
| US-20140140927-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | PSEN1, PSEN2, CROCC | KMT2A 3172/4885MEN1 847/4885ESR1 2852/4885 |
| US-20160263257-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | PSEN1, CROCC, PSEN2 | KMT2A 2976/4885MEN1 468/4885ESR1 2787/4885 |
| US-10245331-B2 | Cromolyn derivatives and related methods of imaging and treatment | PSEN1, PSEN2, CROCC | KMT2A 3196/4885MEN1 889/4885ESR1 2983/4885 |
| US-20180193492-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | PSEN1, PSEN2, CROCC | KMT2A 3445/4885MEN1 970/4885ESR1 3295/4885 |
| US-20120058049-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | CLN6, CA6, GALNT6 | KMT2A 3015/4885MEN1 1337/4885ESR1 3102/4885 |
| US-11666669-B2 | Cromolyn derivatives and related methods of imaging and treatment | PSEN1, PSEN2, CROCC | KMT2A 3172/4885MEN1 847/4885ESR1 2852/4885 |
| US-20180169277-A1 | CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT | PSEN1, PSEN2, CROCC | KMT2A 3196/4885MEN1 889/4885ESR1 2983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.