Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.51 |
| ▸ | PROKR1 | Q8TCW9 | 4/20 | 0.51 |
| ▸ | HRH1 | P35367 | 16/20 | 0.49 |
| ▸ | CCR3 | P51677 | 16/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752287 | 0.89 | FPR2 (0.48) | FPR2PROKR1HRH1CCR3KCNH2 | |
| SCHEMBL4788541 | 0.83 | FPR2 (0.48) | FPR2PROKR1 | |
| SCHEMBL5020189 | 0.82 | FPR2 (0.52) | FPR2PROKR1HRH1CCR3KCNH2 | |
| SCHEMBL5406534 | 0.72 | HRH1 (0.61) | HRH1CCR3KCNH2 | |
| SCHEMBL5020541 | 0.71 | HRH1 (0.47) | FPR2PROKR1HRH1CCR3KCNH2 | |
| SCHEMBL5020187 | 0.71 | FPR2 (0.49) | FPR2PROKR1HRH1CCR3 | |
| SCHEMBL8111588 | 0.70 | HRH1 (0.46) | FPR2PROKR1HRH1CCR3KCNH2 | |
| SCHEMBL5407400 | 0.70 | HRH1 (0.72) | HRH1CCR3KCNH2 | |
| SCHEMBL5411633 | 0.69 | HRH1 (0.71) | HRH1CCR3KCNH2 | |
| SCHEMBL5415137 | 0.69 | HRH1 (0.71) | HRH1CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147764-A1 | MMP INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA, INC. (US) | 2008-12-04 | — | — | WO | claimed |
| WO-2008147764-A1 | MMP INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA, INC. (US) | 2008-12-04 | — | — | WO | disclosed |