Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 18/20 | 0.47 |
| ▸ | CCR3 | P51677 | 18/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.47 |
| ▸ | FPR2 | P25090 | 2/20 | 0.44 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020188 | 0.84 | MMP13 (0.47) | FPR2PROKR1 | |
| SCHEMBL8111588 | 0.78 | HRH1 (0.46) | HRH1CCR3KCNH2FPR2PROKR1 | |
| SCHEMBL4753890 | 0.71 | FPR2 (0.51) | HRH1CCR3KCNH2FPR2PROKR1 | |
| SCHEMBL20997844 | 0.71 | HRH1 (0.40) | HRH1CCR3KCNH2FPR2PROKR1 | |
| SCHEMBL5020189 | 0.70 | FPR2 (0.52) | HRH1CCR3KCNH2FPR2PROKR1 | |
| SCHEMBL8124348 | 0.67 | MMP13 (0.47) | FPR2PROKR1 | |
| SCHEMBL8096418 | 0.66 | FPR2 (0.46) | HRH1CCR3FPR2PROKR1 | |
| SCHEMBL5409384 | 0.66 | HRH1 (0.64) | HRH1CCR3KCNH2FPR2PROKR1 | |
| SCHEMBL5411597 | 0.66 | HRH1 (0.72) | HRH1CCR3KCNH2 | |
| SCHEMBL5406534 | 0.66 | HRH1 (0.61) | HRH1CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064943-A2 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2012-05-18 | — | — | WO | disclosed |