Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 5/20 | 0.48 |
| ▸ | PROKR1 | Q8TCW9 | 5/20 | 0.48 |
| ▸ | MMP13 | P45452 | 5/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752287 | 0.88 | FPR2 (0.48) | FPR2PROKR1MMP13MMP12MAPT | |
| SCHEMBL4753890 | 0.83 | FPR2 (0.51) | FPR2PROKR1 | |
| SCHEMBL8777604 | 0.82 | FPR2 (0.48) | FPR2PROKR1MMP13MMP2MMP12 | |
| SCHEMBL6096681 | 0.73 | FPR2 (0.61) | FPR2PROKR1MMP13MMP2MMP12 | |
| SCHEMBL5020188 | 0.70 | MMP13 (0.47) | FPR2PROKR1MMP13MMP2MMP12 | |
| SCHEMBL29716504 | 0.70 | SMN1; SMN2 (0.61) | FPR2PROKR1MMP13MMP2MMP12 | |
| SCHEMBL8124348 | 0.70 | MMP13 (0.47) | FPR2PROKR1MMP13MMP2MMP12 | |
| SCHEMBL5020187 | 0.69 | FPR2 (0.49) | FPR2PROKR1MMP13MMP12MAPT | |
| SCHEMBL7398293 | 0.68 | MMP13 (0.55) | FPR2PROKR1MMP13MMP2MMP12 | |
| SCHEMBL6098249 | 0.67 | FPR2 (0.56) | FPR2PROKR1MMP13MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147764-A1 | MMP INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA, INC. (US) | 2008-12-04 | — | — | WO | claimed |
| WO-2008147764-A1 | MMP INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA, INC. (US) | 2008-12-04 | — | — | WO | disclosed |
| WO-2008147764-A1 | MMP INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA, INC. (US) | 2008-12-04 | — | — | WO | disclosed |