Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.38 |
| ▸ | HTR3B | O95264 | 3/20 | 0.38 |
| ▸ | HTR3A | P46098 | 3/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 4/20 | 0.37 |
| ▸ | ACVR1B | P36896 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938158 | 0.87 | LMNA (0.52) | LMNAALDH1A1ADRB1HTR3EHTR3B | |
| SCHEMBL3923985 | 0.80 | ALDH1A1 (0.72) | LMNAALDH1A1ADRB1HTR3EHTR3B | |
| SCHEMBL8452388 | 0.69 | ALDH1A1 (0.50) | LMNAALDH1A1ADRB1HTR6HTR2C | |
| SCHEMBL11295127 | 0.69 | ALDH1A1 (0.42) | LMNAALDH1A1ADRB1HTR3EHTR3B | |
| SCHEMBL107339 | 0.69 | HSD17B10 (0.36) | CYP2C9 | |
| SCHEMBL31651833 | 0.67 | ACVR1 (0.43) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL31651688 | 0.66 | LMNA (0.51) | LMNAADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL21359080 | 0.66 | HTR3A (0.49) | LMNAADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL14922725 | 0.66 | ADRB1 (0.61) | LMNAALDH1A1ADRB1HTR3EHTR3B | |
| SCHEMBL6747109 | 0.66 | PDE10A (0.45) | LMNAALDH1A1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146063-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-12-04 | — | — | WO | disclosed |