Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 4/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755359 | 0.94 | PYGL (0.32) | PYGLF11KLKB1 | |
| SCHEMBL4756926 | 0.91 | CTSS (0.35) | — | |
| SCHEMBL4811775 | 0.91 | CTSS (0.35) | — | |
| SCHEMBL4788989 | 0.87 | CTSS (0.34) | — | |
| SCHEMBL498972 | 0.84 | REN (0.43) | — | |
| SCHEMBL498973 | 0.84 | REN (0.43) | — | |
| SCHEMBL499789 | 0.84 | REN (0.43) | — | |
| SCHEMBL499788 | 0.84 | REN (0.43) | — | |
| SCHEMBL4756800 | 0.79 | REN (0.31) | — | |
| SCHEMBL499809 | 0.75 | REN (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156816-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | claimed |