Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4811775 | 1.00 | CTSS (0.35) | CTSSACKR3CHRNA7RENMAPK14 | |
| SCHEMBL4788989 | 0.94 | CTSS (0.34) | CTSSACKR3REN | |
| SCHEMBL4754331 | 0.91 | PYGL (0.32) | — | |
| SCHEMBL4755359 | 0.87 | PYGL (0.32) | — | |
| SCHEMBL499019 | 0.84 | REN (0.43) | CTSSREN | |
| SCHEMBL499018 | 0.84 | REN (0.43) | CTSSREN | |
| SCHEMBL499809 | 0.84 | REN (0.43) | CTSSREN | |
| SCHEMBL499789 | 0.75 | REN (0.43) | REN | |
| SCHEMBL499788 | 0.75 | REN (0.43) | REN | |
| SCHEMBL498972 | 0.75 | REN (0.43) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156816-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | claimed |