Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | STAT1 | P42224 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | GPR183 | P32249 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3877038 | 0.88 | LMNA (0.65) | LMNAGAAALDH1A1STAT1PKM | |
| SCHEMBL4646954 | 0.88 | LMNA (0.65) | LMNAGAAALDH1A1STAT1PKM | |
| SCHEMBL4646949 | 0.88 | LMNA (0.65) | LMNAGAAALDH1A1STAT1PKM | |
| SCHEMBL3932017 | 0.82 | ALDH1A1 (0.55) | GAAALDH1A1STAT1PKMHTT | |
| SCHEMBL587788 | 0.82 | CYP3A4 (0.68) | LMNAGAAALDH1A1PKMMAOA | |
| SCHEMBL22252719 | 0.79 | POLB (0.56) | ALDH1A1POLBSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL1711115 | 0.78 | PKM (0.85) | LMNAALDH1A1PKMPOLBHTT | |
| SCHEMBL4537086 | 0.78 | PKM (0.88) | LMNAGAAALDH1A1PKMPOLB | |
| SCHEMBL10724066 | 0.78 | PKM (0.88) | LMNAGAAALDH1A1PKMPOLB | |
| SCHEMBL8203532 | 0.78 | PKM (0.88) | LMNAGAAALDH1A1PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008155777-A2 | PROCESS FOR PREPARING EFLETRIZINE | CADILA HEALTHCARE LIMITED (IN) | 2008-12-24 | — | — | WO | claimed |
| WO-2008155777-A2 | PROCESS FOR PREPARING EFLETRIZINE | CADILA HEALTHCARE LIMITED (IN) | 2008-12-24 | — | — | WO | disclosed |