Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755826 | 0.77 | NQO2 (0.34) | CYP1A2CYP2D6CYP2C19CLK4TSHR | |
| SCHEMBL856172 | 0.73 | ABCG2 (0.43) | CYP1A2L3MBTL1SMN1; SMN2LMNANPC1 | |
| SCHEMBL17691568 | 0.69 | SMN1; SMN2 (0.57) | CYP1A2CYP2D6CYP2C19CLK4TSHR | |
| SCHEMBL28054676 | 0.69 | LMNA (0.52) | CYP1A2L3MBTL1SMN1; SMN2LMNANPC1 | |
| SCHEMBL18698079 | 0.68 | HPGD (0.51) | CYP1A2L3MBTL1SMN1; SMN2LMNAHPGD | |
| SCHEMBL24729180 | 0.66 | RAB9A (0.45) | TSHRMAPK1L3MBTL1HSD17B10SMN1; SMN2 | |
| SCHEMBL17993428 | 0.65 | L3MBTL1 (0.61) | CYP1A2CYP2D6CYP2C19CLK4TSHR | |
| SCHEMBL18317351 | 0.65 | NQO2 (0.42) | CYP1A2TSHRHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL25107058 | 0.65 | L3MBTL1 (0.55) | CYP1A2CYP2D6CYP2C19CLK4TSHR | |
| SCHEMBL422358 | 0.63 | PDE10A (0.61) | CYP1A2L3MBTL1HSD17B10SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154905-A2 | MODIFICATIONS OF THE HISTONE DEACETYLASE INHIBITOR SUBEROYLANILIDE HYDROXAMIC ACID | SCHEBO BIOTECH AG (DE) | 2008-12-24 | — | — | WO | disclosed |