SCHEMBL4754902

SCHEMBL4754902

Nc1ncnc2c1nc(Sc1ccccc1Cl)n2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC28A2 O43868 6/20 0.64
GAPDH P04406 2/20 0.63
HSD17B10 Q99714 1/20 0.63
HSPA8 P11142 5/20 0.62
HSPA5 P11021 3/20 0.62
ADORA3 P0DMS8 2/20 0.59
RXFP1 Q9HBX9 1/20 0.57
ADORA2A P29274 1/20 0.56
LMNA P02545 1/20 0.55
TP53 P04637 1/20 0.55
HBB P68871 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13835110 0.87 GAPDH (0.70) SLC28A2GAPDHHSD17B10HSPA8HSPA5
SCHEMBL13835106 0.87 GAPDH (0.70) SLC28A2GAPDHHSD17B10HSPA8HSPA5
SCHEMBL30316415 0.85 CYP3A4 (0.67) SLC28A2GAPDHHSD17B10HSPA8HSPA5
SCHEMBL3485985 0.85 CYP3A4 (0.67) SLC28A2GAPDHHSD17B10HSPA8HSPA5
SCHEMBL578218 0.85 CYP3A4 (0.67) SLC28A2GAPDHHSD17B10HSPA8HSPA5
SCHEMBL7258733 0.84 HSPA8 (0.68) SLC28A2GAPDHHSD17B10HSPA8HSPA5
SCHEMBL6758574 0.81 HSD17B10 (0.68) SLC28A2GAPDHHSD17B10HSPA8HSPA5
SCHEMBL7258948 0.81 HSPA8 (0.66) SLC28A2GAPDHHSD17B10HSPA8HSPA5
SCHEMBL7258957 0.81 HSPA8 (0.66) SLC28A2GAPDHHSD17B10HSPA8HSPA5
SCHEMBL6758562 0.81 HSD17B10 (0.68) SLC28A2GAPDHHSD17B10HSPA8HSPA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008153881-A1 NOVEL CELL-BASED ASSAYS FOR INDENTIFYING ENHANCERS OR INHIBITORS OF T1R TASTE RECEPTORS (T1R2/T1R3 SWEET) AND UMAMI (T1R1/T1R3 UMAMI) TASTE RECEPTORS SENOMYX, INC. (US) 2008-12-18 WO claimed