Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.45 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.43 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.43 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758239 | 0.82 | MAPK14 (0.47) | DDR1HDAC3HDAC8PLOD2PLOD3 | |
| SCHEMBL545939 | 0.81 | TPMT (0.52) | RAB9APLOD2PLOD3PLOD1KDM4E | |
| SCHEMBL1482084 | 0.81 | BCL2A1 (0.44) | DDR1RAB9APLOD2PLOD3PLOD1 | |
| Hydrochloric Acid SCHEMBL2327804 | 0.80 | BCL2A1 (0.43) | DDR1RAB9APLOD2PLOD3PLOD1 | |
| SCHEMBL18352938 | 0.79 | PLOD2 (0.62) | RAB9AHDAC3HDAC8PLOD2PLOD3 | |
| SCHEMBL5639759 | 0.78 | HDAC3 (0.68) | RAB9AHDAC3HDAC8NPC1KMT2A | |
| SCHEMBL4757779 | 0.78 | HDAC3 (0.44) | DDR1HDAC3HDAC8KMT2ALMNA | |
| SCHEMBL4756997 | 0.77 | MEN1 (0.48) | ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL8318081 | 0.77 | BCL2A1 (0.59) | RAB9AKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL2635338 | 0.75 | KDM4E (0.61) | RAB9AKDM4EALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |