Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755106 | 0.85 | PIK3CA (0.55) | MEN1KMT2AMAPK1LMNAMAPT | |
| SCHEMBL8698788 | 0.81 | PLOD2 (0.56) | MEN1KMT2ACYP2C9MAPK1LMNA | |
| SCHEMBL4757779 | 0.80 | HDAC3 (0.44) | MEN1KMT2AWDR5MAPK1LMNA | |
| SCHEMBL5324137 | 0.80 | CYP2C9 (0.62) | MEN1KMT2ACYP2C9LMNAMAPT | |
| SCHEMBL1482084 | 0.79 | BCL2A1 (0.44) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL545939 | 0.79 | TPMT (0.52) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7589274 | 0.78 | CA12 (0.62) | MEN1KMT2ACYP2C9LMNACA12 | |
| SCHEMBL2662880 | 0.78 | CA12 (0.62) | MEN1KMT2ACYP2C9LMNACA12 | |
| Hydrochloric Acid SCHEMBL2327804 | 0.78 | BCL2A1 (0.43) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL4755079 | 0.77 | DDR1 (0.47) | KMT2ALMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |