Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | RPA1 | P27694 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755075 | 1.00 | AVPR1A (0.37) | AVPR1ALDHANOTUMPSDKDM4E | |
| SCHEMBL13985224 | 0.88 | TBK1 (0.33) | AVPR1ATBK1GRM5 | |
| SCHEMBL4755635 | 0.83 | AVPR1A (0.38) | AVPR1ANOTUMKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4755639 | 0.83 | AVPR1A (0.38) | AVPR1ANOTUMKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4789685 | 0.83 | AVPR1A (0.39) | AVPR1APSDKDM4EMAPTALDH1A1 | |
| SCHEMBL13985222 | 0.83 | AVPR1A (0.39) | AVPR1AKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4755169 | 0.83 | AVPR1A (0.39) | AVPR1AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4755166 | 0.83 | AVPR1A (0.39) | AVPR1AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4755067 | 0.83 | AVPR1A (0.37) | AVPR1ANOTUMKDM4EMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL4755710 | 0.82 | AVPR1A (0.38) | AVPR1AKDM4EMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |