SCHEMBL7626430

SCHEMBL7626430

CCCCc1cc(C(C)CC)cc(C(C)c2cc(C(C)CC)cc(CCCC)c2O)c1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.37
ALOX5 P09917 5/20 0.36
ALOX15 P16050 2/20 0.35
HPGD P15428 2/20 0.35
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
PKM P14618 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PTGS2 P35354 3/20 0.35
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
EGFR P00533 1/20 0.33
TSHR P16473 2/20 0.33
HTT P42858 2/20 0.32
CYP3A4 P08684 2/20 0.32
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8037388 0.89 TYR (0.42) TYRALOX5ALOX15HPGDUSP2
SCHEMBL27803636 0.84 TYR (0.42) TYRALOX5ALOX15HPGDUSP2
SCHEMBL13929512 0.83 TYR (0.38) TYRALOX5ALOX15HPGDUSP2
SCHEMBL12670028 0.81 MAOA (0.33) ALDH1A1
SCHEMBL4755155 0.79 GABRA1 (0.52) TYRALOX5PTGS2CYP2D6
SCHEMBL3898876 0.79 NPC1 (0.46) TYRALOX5HPGDPTGS2HTT
SCHEMBL3807221 0.79 TYR (0.40) TYRALOX5ALOX15HPGDALDH1A1
SCHEMBL6744605 0.78 TSHR (0.44) ALOX15HPGDUSP2ALDH1A1GAA
SCHEMBL14087094 0.78 ALOX5 (0.47) TYRALOX5ALOX15ALDH1A1GAA
SCHEMBL12661843 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1033243-B1 Aromatic polycarbonate resin coextruded article ASAHI DENKA KOGYO KK (JP) 2002-06-12 EP disclosed
US-6333114-B1 WEATHERABILITY AND IMPROVED COLORING RESISTANCE; FOR PRODUCING MOLDED ARTICLES SUCH AS FOOD PACKAGING CONTAINERS, INTERIOR AND EXTERIOR AUTOMOTIVE TRIM PARTS, AND PRECISION MACHINES, FILMS ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 2001-12-25 US disclosed
EP-1033243-A1 Aromatic polycarbonate resin coextruded article ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 2000-09-06 EP disclosed
US-5238979-A Bisphenol phosphites and a phenol ASAHI DENKA KOGYO K.K. (JP) 1993-08-24 US disclosed
US-5112891-A Cyclic Phosphite Heat Stabilizer ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1992-05-12 US disclosed
US-5055507-A Bisphenol phosphite/phenol mixture for enhancing heat and radiation resistance ASAHI DENKA KOGYO K.K. (JP) 1991-10-08 US disclosed
EP-0395030-A1 Polyolefin resins containing ziegler type complex catalyst residues stabilized with organic phosphites ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1990-10-31 EP disclosed
US-4670492-A Cyclic bis and tris phosphites and stabilized synthetic resin compositions ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1987-06-02 US disclosed
EP-0128229-A1 Hindered bisphenol diphosphonites and stabilized synthetic resin compositions containing the same ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1984-12-19 EP disclosed
US-4481317-A HEAT RESISTANCE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1984-11-06 US disclosed