Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCAT | P04180 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | USP14 | P54578 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ERG | P11308 | 1/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985513 | 1.00 | LCAT (0.35) | LCATARPDE4BPDE4DUSP14 | |
| SCHEMBL13985505 | 0.82 | MCHR1 (0.35) | HRH3 | |
| SCHEMBL4790013 | 0.82 | MCHR1 (0.35) | HRH3 | |
| SCHEMBL13985419 | 0.81 | PDE4B (0.34) | LCATARPDE4BPDE4DUSP14 | |
| SCHEMBL4755607 | 0.77 | PDE4B (0.34) | LCATARPDE4BPDE4DUSP14 | |
| SCHEMBL13985423 | 0.77 | PDE4B (0.34) | LCATARPDE4BPDE4DUSP14 | |
| SCHEMBL4755767 | 0.75 | CHRNB2 (0.34) | USP14PIK3CA | |
| SCHEMBL4755765 | 0.75 | CHRNB2 (0.34) | USP14PIK3CA | |
| SCHEMBL4789984 | 0.75 | KCNH2 (0.32) | LCATCYP3A4ERGGPBAR1 | |
| SCHEMBL4755652 | 0.75 | PDE4B (0.35) | LCATPDE4BPDE4DUSP14PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |