Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | LCAT | P04180 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ERG | P11308 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755651 | 0.86 | SPR (0.32) | PDE1APDE1BPDE1CSPR | |
| SCHEMBL13985520 | 0.84 | USP14 (0.38) | KCNH2 | |
| SCHEMBL4755767 | 0.81 | CHRNB2 (0.34) | SPR | |
| SCHEMBL4755765 | 0.81 | CHRNB2 (0.34) | SPR | |
| SCHEMBL4755215 | 0.80 | DRD1 (0.40) | CYP3A4 | |
| SCHEMBL4755592 | 0.80 | DRD1 (0.37) | — | |
| SCHEMBL4755213 | 0.80 | DRD1 (0.40) | CYP3A4 | |
| SCHEMBL4755594 | 0.80 | DRD1 (0.37) | — | |
| SCHEMBL4755659 | 0.79 | MEN1 (0.39) | — | |
| SCHEMBL4755656 | 0.79 | MEN1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |