Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 2/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755765 | 1.00 | CHRNB2 (0.34) | CHRNB2CHRNA4PIK3CAAVPR1AUSP14 | |
| SCHEMBL4755651 | 0.88 | SPR (0.32) | AVPR1ASPR | |
| SCHEMBL4755169 | 0.87 | AVPR1A (0.39) | AVPR1AMCHR1 | |
| SCHEMBL4755166 | 0.87 | AVPR1A (0.39) | AVPR1AMCHR1 | |
| SCHEMBL13985224 | 0.85 | TBK1 (0.33) | CHRNB2CHRNA4PIK3CAAVPR1AUSP14 | |
| SCHEMBL4755592 | 0.84 | DRD1 (0.37) | MAT2A | |
| SCHEMBL4755594 | 0.84 | DRD1 (0.37) | MAT2A | |
| SCHEMBL4753522 | 0.84 | SPR (0.32) | AVPR1ASPR | |
| SCHEMBL4755659 | 0.83 | MEN1 (0.39) | MCHR1 | |
| SCHEMBL4755656 | 0.83 | MEN1 (0.39) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |