Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222150 | 0.87 | TSHR (0.64) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL18209598 | 0.85 | RAB9A (0.69) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL11672937 | 0.84 | LMNA (0.46) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL6900571 | 0.82 | KMT2A (0.58) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL4755619 | 0.82 | TSHR (0.54) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL1221272 | 0.82 | TSHR (0.54) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL2742818 | 0.82 | HPGD (0.70) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL9500449 | 0.80 | HPGD (0.74) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL8052120 | 0.80 | NPSR1 (0.59) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL9699014 | 0.79 | ALDH1A1 (0.64) | ALDH1A1HPGDMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157844-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-12-24 | — | — | WO | disclosed |