Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21784421 | 0.90 | KMT2A (0.61) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL19187414 | 0.86 | L3MBTL1 (0.56) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4924913 | 0.85 | MEN1 (0.60) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| Ethyl Benzoate SCHEMBL27869298 | 0.85 | ALDH1A1 (0.62) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL27403334 | 0.84 | SMN1; SMN2 (0.50) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| Ethyl Benzoate SCHEMBL21531031 | 0.84 | LMNA (0.63) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| Ethyl Benzoate SCHEMBL28029820 | 0.84 | LMNA (0.68) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| Benzene SCHEMBL27873122 | 0.84 | CA1 (0.76) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| Benzoyl Peroxide SCHEMBL32689642 | 0.83 | ALDH1A1 (0.64) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| Benzoic Acid SCHEMBL5190239 | 0.83 | ALDH1A1 (0.64) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013787-B1 | TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES | COUNCIL SCIENT IND RES (IN) | 2017-08-02 | — | — | EP | disclosed |
| EP-3013787-B1 | TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES | COUNCIL SCIENT IND RES (IN) | 2017-08-02 | — | — | EP | disclosed |
| US-9650329-B2 | Transition-metal-free N-arylation of tertiary amines using arynes | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-05-16 | — | — | US | disclosed |
| US-9650329-B2 | Transition-metal-free N-arylation of tertiary amines using arynes | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-05-16 | — | — | US | disclosed |
| US-20160137587-A1 | TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-05-19 | — | — | US | disclosed |
| US-20160137587-A1 | TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-05-19 | — | — | US | disclosed |
| EP-3013787-A1 | TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES | Council of Scientific & Industrial Research (IN) | 2016-05-04 | — | — | EP | disclosed |
| WO-2014207761-A1 | TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-12-31 | — | — | WO | disclosed |
| EP-1100485-A4 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2004-06-09 | — | — | EP | disclosed |
| EP-1100485-A1 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006146-A9 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORP (US) | 2000-08-03 | — | — | WO | disclosed |
| WO-2000006146-A1 | SUBSTITUTED ANILIDE COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137587-A1 | TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES | CDK6, NEK6, MCM6 | KMT2A 156/4885MEN1 3294/4885SMN1; SMN2 3941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.