Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6619906 | 0.74 | ADORA2A (0.43) | KMT2AMEN1RAB9AALDH1A1NPC1 | |
| SCHEMBL457982 | 0.71 | RAB9A (0.44) | L3MBTL1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL4755835 | 0.67 | NPC1 (0.48) | L3MBTL1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL15253853 | 0.67 | GABRA1 (0.42) | L3MBTL1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL2909035 | 0.65 | L3MBTL1 (0.44) | L3MBTL1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL2493590 | 0.65 | RAB9A (0.62) | L3MBTL1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL2909003 | 0.64 | MEN1 (0.52) | L3MBTL1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL8475027 | 0.64 | BRD4 (0.42) | L3MBTL1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL637345 | 0.64 | MEN1 (0.43) | L3MBTL1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL1316597 | 0.64 | RAB9A (0.48) | L3MBTL1KMT2AMEN1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154905-A2 | MODIFICATIONS OF THE HISTONE DEACETYLASE INHIBITOR SUBEROYLANILIDE HYDROXAMIC ACID | SCHEBO BIOTECH AG (DE) | 2008-12-24 | — | — | WO | disclosed |