Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755791 | 0.74 | L3MBTL1 (0.39) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL2493590 | 0.65 | RAB9A (0.62) | ADORA2AADORA1ALDH1A1SMARCA2SMARCA4 | |
| SCHEMBL2909003 | 0.64 | MEN1 (0.52) | ADORA2AADORA1ALDH1A1MAPTAGTR1 | |
| SCHEMBL1316597 | 0.64 | RAB9A (0.48) | ADORA2AADORA1ASIC3ALDH1A1MAPT | |
| SCHEMBL220069 | 0.64 | SMARCA2 (0.52) | ADORA2AADORA1ASIC3ALDH1A1MAPT | |
| SCHEMBL4053052 | 0.62 | MAP2K3 (0.56) | ADORA2AADORA1ASIC3ALDH1A1MAPT | |
| SCHEMBL69333 | 0.62 | LDHA (0.52) | ADORA2AADORA1ASIC3ALDH1A1MAPT | |
| SCHEMBL557899 | 0.62 | KMT2A (0.41) | ADORA2AADORA1ASIC3ALDH1A1HSP90AA1 | |
| SCHEMBL13458070 | 0.61 | RAB9A (0.58) | ALDH1A1MAPTSMARCA2SMARCA4PBRM1 | |
| SCHEMBL4904514 | 0.61 | ADORA2A (1.00) | ADORA2AADORA1ALDH1A1MAPTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891332-B1 | 6-PHENYLPYRIDYL-2-AMINE DERIVATIVES | PFIZER (US) | 2004-03-17 | — | — | EP | disclosed |