Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | PPARA | Q07869 | 4/20 | 0.60 |
| ▸ | PPARG | P37231 | 3/20 | 0.60 |
| ▸ | LTA4H | P09960 | 2/20 | 0.60 |
| ▸ | PPARD | Q03181 | 1/20 | 0.60 |
| ▸ | LAP3 | P28838 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375675 | 1.00 | L3MBTL1 (0.65) | L3MBTL1LMNAPPARAPPARGLTA4H | |
| SCHEMBL1596779 | 1.00 | L3MBTL1 (0.65) | L3MBTL1LMNAPPARAPPARGLTA4H | |
| SCHEMBL27854776 | 0.90 | LTA4H (0.71) | LMNAPPARAPPARGLTA4HPPARD | |
| SCHEMBL6738407 | 0.89 | LTA4H (0.57) | L3MBTL1LMNAPPARAPPARGLTA4H | |
| SCHEMBL6738411 | 0.89 | LTA4H (0.57) | L3MBTL1LMNAPPARAPPARGLTA4H | |
| SCHEMBL4755605 | 0.89 | L3MBTL1 (0.52) | L3MBTL1LMNAPPARAPPARGLTA4H | |
| SCHEMBL2164928 | 0.87 | LTA4H (0.72) | PPARAPPARGLTA4HPPARDLAP3 | |
| SCHEMBL6732617 | 0.87 | LTA4H (0.72) | PPARAPPARGLTA4HPPARDLAP3 | |
| SCHEMBL9493387 | 0.87 | L3MBTL1 (0.67) | L3MBTL1LMNAPPARAPPARGLTA4H | |
| SCHEMBL5309375 | 0.87 | LTA4H (0.72) | PPARAPPARGLTA4HPPARDLAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |