Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | PPARA | Q07869 | 4/20 | 0.61 |
| ▸ | PPARG | P37231 | 3/20 | 0.61 |
| ▸ | PPARD | Q03181 | 1/20 | 0.61 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.58 |
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LAP3 | P28838 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15707904 | 0.96 | LMNA (0.62) | L3MBTL1LMNAPPARAPPARGPPARD | |
| SCHEMBL27385612 | 0.96 | LMNA (0.65) | L3MBTL1LMNAPPARAPPARGPPARD | |
| SCHEMBL4855268 | 0.93 | LMNA (0.62) | L3MBTL1LMNAPPARAPPARGPPARD | |
| SCHEMBL27461095 | 0.91 | LMNA (0.57) | L3MBTL1LMNAPPARAPPARGPPARD | |
| SCHEMBL27539789 | 0.89 | L3MBTL1 (0.61) | L3MBTL1LMNAPPARAPPARGPPARD | |
| SCHEMBL1596779 | 0.87 | L3MBTL1 (0.65) | L3MBTL1LMNAPPARAPPARGPPARD | |
| SCHEMBL4756342 | 0.87 | L3MBTL1 (0.65) | L3MBTL1LMNAPPARAPPARGPPARD | |
| SCHEMBL5375675 | 0.87 | L3MBTL1 (0.65) | L3MBTL1LMNAPPARAPPARGPPARD | |
| SCHEMBL165382 | 0.86 | MMP8 (0.76) | L3MBTL1LMNAPPARGMMP8ALDH1A1 | |
| SCHEMBL7492211 | 0.86 | L3MBTL1 (0.64) | L3MBTL1LMNAPPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254080-B1 | MALONIC ACID DERIVATIVES AND METHODS FOR THEIR SYNTHESIS | ENIRICERCHE S.p.A. (IT) | 1993-03-17 | — | — | EP | disclosed |
| US-4914226-A | Malonic acid derivatives and methods for their synthesis | ENIRICERCHE S.P.A. (IT) | 1990-04-03 | — | — | US | disclosed |
| EP-0254080-A2 | Malonic acid derivatives and methods for their synthesis | ENIRICERCHE S.p.A. (IT) | 1988-01-27 | — | — | EP | disclosed |