Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 8/20 | 0.34 |
| ▸ | GSK3B | P49841 | 12/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756814 | 0.91 | GSK3B (0.33) | RENGSK3B | |
| SCHEMBL4755820 | 0.87 | REN (0.35) | REN | |
| SCHEMBL4754633 | 0.78 | CTSD (0.33) | REN | |
| SCHEMBL4757259 | 0.77 | REN (0.36) | REN | |
| SCHEMBL4525603 | 0.77 | REN (0.36) | REN | |
| SCHEMBL4754635 | 0.75 | — | — | |
| SCHEMBL4756492 | 0.73 | REN (0.43) | REN | |
| SCHEMBL8468872 | 0.73 | REN (0.43) | REN | |
| SCHEMBL8476452 | 0.70 | REN (0.45) | REN | |
| SCHEMBL4755815 | 0.70 | REN (0.45) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1911762-A1 | Amino alcohols and their use as renin inhibitors | Speedel Experimenta AG (CH) | 2008-04-16 | — | — | EP | disclosed |