Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 8/20 | 0.35 |
| ▸ | HTR1D | P28221 | 3/20 | 0.34 |
| ▸ | HTR1B | P28222 | 3/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | NMBR | P28336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754633 | 0.90 | CTSD (0.33) | RENHTR1DHTR1BHTR4ALDH1A1 | |
| SCHEMBL4756494 | 0.87 | REN (0.34) | REN | |
| SCHEMBL4757259 | 0.79 | REN (0.36) | REN | |
| SCHEMBL4756814 | 0.78 | GSK3B (0.33) | RENALDH1A1 | |
| SCHEMBL1047567 | 0.78 | HTR1D (0.39) | HTR1DHTR1BALDH1A1MTNR1AMTNR1B | |
| SCHEMBL3769416 | 0.77 | HTR1D (0.38) | RENHTR1DHTR1BMTNR1AMTNR1B | |
| SCHEMBL4539260 | 0.77 | HTR1D (0.38) | RENHTR1DHTR1BMTNR1AMTNR1B | |
| SCHEMBL1049891 | 0.75 | MTNR1A (0.35) | ALDH1A1MTNR1AMTNR1BPTGS2TRPV1 | |
| SCHEMBL5050472 | 0.75 | HTR1D (0.35) | HTR1DHTR1BALDH1A1MTNR1AMTNR1B | |
| SCHEMBL3769452 | 0.74 | REN (0.33) | RENHTR1DHTR1BSPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1911762-A1 | Amino alcohols and their use as renin inhibitors | Speedel Experimenta AG (CH) | 2008-04-16 | — | — | EP | disclosed |