Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.33 |
| ▸ | CTSD | P07339 | 2/20 | 0.33 |
| ▸ | REN | P00797 | 3/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | CTSE | P14091 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756494 | 0.91 | REN (0.34) | GSK3BREN | |
| SCHEMBL4754633 | 0.88 | CTSD (0.33) | CTSDRENF10PRSS1ALDH1A1 | |
| SCHEMBL4757263 | 0.79 | REN (0.33) | CTSDRENF10PRSS1ALDH1A1 | |
| SCHEMBL4755820 | 0.78 | REN (0.35) | RENALDH1A1 | |
| SCHEMBL4756821 | 0.75 | REN (0.40) | REN | |
| SCHEMBL8471863 | 0.75 | REN (0.40) | REN | |
| SCHEMBL4525603 | 0.73 | REN (0.36) | REN | |
| SCHEMBL4754635 | 0.73 | — | — | |
| SCHEMBL8469012 | 0.72 | REN (0.42) | REN | |
| SCHEMBL4754622 | 0.72 | REN (0.42) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154905-A2 | MODIFICATIONS OF THE HISTONE DEACETYLASE INHIBITOR SUBEROYLANILIDE HYDROXAMIC ACID | SCHEBO BIOTECH AG (DE) | 2008-12-24 | — | — | WO | disclosed |