SCHEMBL4756591

SCHEMBL4756591

[CH2]COC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2292571 0.91 SOAT1 (0.30)
SCHEMBL14063664 0.83 MGLL (0.33) MGLL
SCHEMBL8035936 0.82 MGLL (0.32) MGLL
SCHEMBL17447 0.80 MGLL (0.37) MGLL
SCHEMBL1799869 0.80 ALDH1A1 (0.46)
SCHEMBL5395199 0.80 MGLL (0.34) MGLL
SCHEMBL1111161 0.79 CYP3A4 (0.37)
SCHEMBL19175330 0.79
SCHEMBL1949595 0.78 ALOX12 (0.38) MGLL
SCHEMBL13748507 0.78 ALOX12 (0.38) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107002068-B Therapeutic agents inducing cytotoxicity 中外制药株式会社 2021-07-09 CN disclosed
WO-2017023774-A9 PRODRUGS OF GLUTAMINE ANALOGS THE JOHNS HOPKINS UNIVERSITY (US) 2017-11-23 WO disclosed
WO-2008013860-A2 ACYLOXYALKYL CARBAMATE PRODRUGS OF ALPHA-AMINO ACIDS, METHODS OF SYNTHESIS AND USE XENOPORT, INC. (US) 2008-01-31 WO disclosed
WO-1995031459-A1 MORPHOLINO-SUBUNIT COMBINATORIAL LIBRARY AND METHOD ANTIVIRALS INC. (US) 1995-11-23 WO disclosed