Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23608353 | 0.86 | ALOX12 (0.30) | MGLL | |
| SCHEMBL14063664 | 0.85 | MGLL (0.33) | MGLL | |
| SCHEMBL17447 | 0.82 | MGLL (0.37) | MGLL | |
| SCHEMBL5395199 | 0.82 | MGLL (0.34) | MGLL | |
| SCHEMBL1799869 | 0.82 | ALDH1A1 (0.46) | — | |
| SCHEMBL4756591 | 0.82 | MGLL (0.31) | MGLL | |
| SCHEMBL2781450 | 0.81 | HTT (0.38) | — | |
| SCHEMBL1949595 | 0.80 | ALOX12 (0.38) | MGLL | |
| SCHEMBL15583430 | 0.80 | MGLL (0.31) | MGLL | |
| SCHEMBL13057087 | 0.80 | ADORA3 (0.33) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194500-A1 | Preferably polyethylene glycol etherified by an aliphatic alcohol and a perfluorodiol attached to a di-stearoyl glycerophosphatidylethanolamine; improved water solubility and decreased toxicity of paclitaxel, rapamycin, geldanamycin, doxorubicin, or amphotericin B | NATIONAL SCIENCE FOUNDATION | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194500-A1 | Preferably polyethylene glycol etherified by an aliphatic alcohol and a perfluorodiol attached to a di-stearoyl glycerophosphatidylethanolamine; improved water solubility and decreased toxicity of paclitaxel, rapamycin, geldanamycin, doxorubicin, or amphotericin B | PHOSPHO1, FIBP, SGMS2 | MGLL 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.