Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1447851 | 1.00 | L3MBTL3 (0.49) | L3MBTL3L3MBTL1HPGDPOLBKMT2A | |
| SCHEMBL1447390 | 0.87 | MGLL (0.46) | L3MBTL3L3MBTL1POLBKMT2ACA12 | |
| SCHEMBL4789066 | 0.87 | MGLL (0.46) | L3MBTL3L3MBTL1POLBKMT2ACA12 | |
| SCHEMBL1447659 | 0.87 | MGLL (0.46) | L3MBTL3L3MBTL1POLBKMT2ACA12 | |
| SCHEMBL3405472 | 0.86 | ACHE (0.54) | L3MBTL3L3MBTL1HPGDKMT2ALMNA | |
| SCHEMBL3405466 | 0.86 | ACHE (0.54) | L3MBTL3L3MBTL1HPGDKMT2ALMNA | |
| SCHEMBL10098900 | 0.85 | SMN1; SMN2 (0.52) | HPGDPOLBKMT2ALMNAMGLL | |
| SCHEMBL967428 | 0.83 | L3MBTL3 (0.54) | L3MBTL3L3MBTL1HPGDPOLBKMT2A | |
| SCHEMBL967429 | 0.83 | L3MBTL3 (0.54) | L3MBTL3L3MBTL1HPGDPOLBKMT2A | |
| SCHEMBL4752620 | 0.78 | MGLL (0.39) | L3MBTL3MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912974-A1 | IMIDAZOLYL-PYRIMIDINE COMPOUNDS FOR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS | AstraZeneca AB (SE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007015064-A1 | IMIDAZOLYL-PYRIMIDINE COMPOUNDS FOR USE IN THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2007-02-08 | — | — | WO | disclosed |