Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 8/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1806989 | 0.82 | FPR2 (0.49) | MEN1ALDH1A1KMT2AEPHX2 | |
| SCHEMBL1808242 | 0.75 | MEN1 (0.51) | MEN1ALDH1A1KMT2AEPHX2 | |
| SCHEMBL1809425 | 0.75 | MGLL (0.45) | MEN1ALDH1A1KMT2A | |
| SCHEMBL2636514 | 0.74 | EPHX2 (0.62) | SCDEPHX2 | |
| SCHEMBL2636776 | 0.73 | EPHX2 (0.58) | SCDEPHX2 | |
| SCHEMBL1807517 | 0.73 | MMP13 (0.45) | MEN1ALDH1A1KMT2AEPHX2 | |
| SCHEMBL13149845 | 0.72 | ALDH1A1 (0.52) | MEN1ALDH1A1KMT2A | |
| SCHEMBL22278119 | 0.72 | EPHX2 (0.52) | SCDEPHX2 | |
| SCHEMBL1009838 | 0.71 | EPHX2 (0.56) | SCDEPHX2 | |
| SCHEMBL22446340 | 0.71 | EPHX2 (0.56) | SCDEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987037-A2 | FUSED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007097470-A2 | FUSED NITROGEN- COMPRISING HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-30 | — | — | WO | disclosed |