Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | AURKA | O14965 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209448 | 0.87 | POLB (0.52) | POLBL3MBTL1AURKAKDM4EALDH1A1 | |
| SCHEMBL2731281 | 0.83 | ALDH1A1 (0.52) | POLBL3MBTL1ALDH1A1MAPTNPBWR1 | |
| SCHEMBL207969 | 0.83 | AURKA (0.46) | POLBL3MBTL1AURKAKDM4EALDH1A1 | |
| SCHEMBL209785 | 0.82 | AURKA (0.47) | POLBL3MBTL1AURKAKDM4EALDH1A1 | |
| SCHEMBL210615 | 0.82 | KDM4E (0.44) | L3MBTL1KDM4EALDH1A1MAPTNPBWR1 | |
| SCHEMBL208800 | 0.81 | AURKA (0.43) | POLBL3MBTL1AURKAALDH1A1MAPT | |
| SCHEMBL208825 | 0.80 | MAPT (0.45) | POLBL3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL209309 | 0.80 | TRPV6 (0.41) | L3MBTL1AURKAALDH1A1MAPTNPBWR1 | |
| SCHEMBL210022 | 0.79 | AURKA (0.52) | AURKA | |
| SCHEMBL4757730 | 0.79 | DRD2 (0.38) | POLBL3MBTL1AURKAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001021-A1 | IMIDAZOPYRIDINE DERIVATIVES USEFUL AS ENZYME INHIBITORS FOR THE TREATMENT OF CELL PROLIFERATIVE AND AUTOIMMUNE DISEASES | CHROMA THERAPEUTICS LTD. (GB) | 2008-12-31 | — | — | WO | disclosed |