Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.40 |
| ▸ | CTSB | P07858 | 14/20 | 0.40 |
| ▸ | CTSL | P07711 | 10/20 | 0.40 |
| ▸ | CTSK | P43235 | 14/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699320 | 1.00 | CTSS (0.40) | CTSSCTSBCTSLCTSK | |
| SCHEMBL4702476 | 0.85 | CTSK (0.40) | CTSSCTSBCTSLCTSK | |
| SCHEMBL4699876 | 0.84 | CTSS (0.40) | CTSSCTSBCTSLCTSK | |
| SCHEMBL4698762 | 0.81 | CTSK (0.43) | CTSSCTSBCTSLCTSK | |
| SCHEMBL4704053 | 0.81 | CTSL (0.42) | CTSSCTSBCTSLCTSK | |
| SCHEMBL4701372 | 0.80 | CTSL (0.43) | CTSSCTSBCTSLCTSK | |
| SCHEMBL4703410 | 0.79 | CTSS (0.42) | CTSSCTSBCTSLCTSK | |
| SCHEMBL4701788 | 0.79 | CTSS (0.43) | CTSSCTSBCTSLCTSK | |
| SCHEMBL4699916 | 0.79 | CTSB (0.54) | CTSSCTSBCTSLCTSK | |
| SCHEMBL4699833 | 0.78 | CTSS (0.44) | CTSSCTSBCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372655-B1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA LTD (CA) | 2008-10-01 | — | — | EP | claimed |