Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | STAT3 | P40763 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10114726 | 0.87 | NPC1 (0.37) | NPC1RAB9AALDH1A1STAT3SMN1; SMN2 | |
| SCHEMBL4756608 | 0.85 | ALDH1A1 (0.41) | NPC1RAB9AALDH1A1STAT3SMN1; SMN2 | |
| SCHEMBL4757439 | 0.82 | ALDH1A1 (0.42) | NPC1RAB9AALDH1A1STAT3SMN1; SMN2 | |
| SCHEMBL4757435 | 0.77 | ALDH1A1 (0.44) | NPC1RAB9AALDH1A1STAT3SMN1; SMN2 | |
| SCHEMBL4757479 | 0.76 | KCNMA1 (0.46) | NPC1RAB9AALDH1A1STAT3SMN1; SMN2 | |
| SCHEMBL4757427 | 0.76 | ALDH1A1 (0.47) | NPC1RAB9AALDH1A1STAT3SMN1; SMN2 | |
| SCHEMBL4757381 | 0.75 | STAT3 (0.60) | NPC1RAB9AALDH1A1STAT3SMN1; SMN2 | |
| SCHEMBL4756770 | 0.74 | RAB9A (0.45) | NPC1RAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4757379 | 0.73 | STAT3 (0.56) | NPC1RAB9AALDH1A1STAT3SMN1; SMN2 | |
| SCHEMBL10114130 | 0.73 | FFAR2 (0.40) | NPC1RAB9AALDH1A1STAT3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895752-B2 | Alkylsulfonyl-substituted thiazolide compounds | ROMARK LABORATORIES L.C. (US) | 2014-11-25 | — | — | US | disclosed |
| US-20120122939-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES, L.C. | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122939-A1 | ALKYLSULFONYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | HAVCR2, EIF2AK2, AADAC | NPC1 585/4885RAB9A 1694/4885ALDH1A1 1605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.