Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 4/20 | 0.35 |
| ▸ | CES1 | P23141 | 4/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL4758122 | 0.90 | FAAH (0.39) | FAAHSOAT1MEN1TP53CYP1A2 | |
| Monoethanolamine SCHEMBL4759394 | 0.88 | FAAH (0.38) | FAAHSOAT1MEN1TP53CYP1A2 | |
| SCHEMBL4903344 | 0.78 | CA4 (0.33) | MEN1KMT2ACA2 | |
| Cetyl Alcohol SCHEMBL17986422 | 0.77 | CA2 (0.41) | MEN1KMT2ACA2GPR84CA1 | |
| Oleamide SCHEMBL1258565 | 0.77 | FAAH (0.51) | FAAHSOAT1MEN1TP53CYP1A2 | |
| Oleamide SCHEMBL1258566 | 0.77 | FAAH (0.51) | FAAHSOAT1MEN1TP53CYP1A2 | |
| Monoethanolamine SCHEMBL4758116 | 0.77 | SOAT1 (0.40) | FAAHSOAT1MEN1TP53CYP1A2 | |
| Palmitamide SCHEMBL18210347 | 0.76 | SOAT1 (0.61) | FAAHSOAT1MEN1TP53CYP1A2 | |
| Octadecanoic Acid Amide SCHEMBL943978 | 0.76 | SOAT1 (0.61) | FAAHSOAT1MEN1TP53CYP1A2 | |
| Octadecanoic Acid Amide SCHEMBL1262909 | 0.75 | TP53 (0.42) | FAAHSOAT1MEN1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866519-B1 | METHOD OF RECYCLING FRACTURING FLUIDS USING A SELF-DEGRADING FOAMING COMPOSITION | RHODIA (US) | 2012-08-08 | — | — | EP | disclosed |
| US-20080200351-A1 | Method of recycling fracturing fluids using a self-degrading foaming composition | DAHANAYAKE MANILAL S | 2008-08-21 | — | — | US | disclosed |
| US-7404442-B2 | Method of recycling fracturing fluids using a self-degrading foaming composition | RHODIA INC. (US) | 2008-07-29 | — | — | US | disclosed |
| EP-1866519-A2 | METHOD OF RECYCLING FRACTURING FLUIDS USING A SELF-DEGRADING FOAMING COMPOSITION | RHODIA INC. (US) | 2007-12-19 | — | — | EP | disclosed |
| US-20060260815-A1 | Method of recycling fracturing fluids using a self-degrading foaming composition | RHODIA OPERATIONS (FR) | 2006-11-23 | — | — | US | disclosed |
| WO-2006108161-A2 | METHOD OF RECYCLING FRACTURING FLUIDS USING A SELF-DEGRADING FOAMING COMPOSITION | RHODIA INC. (US) | 2006-10-12 | — | — | WO | disclosed |