Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758299 | 0.87 | LMNA (0.42) | ALDH1A1KMT2AMEN1LMNAPKM | |
| SCHEMBL4758044 | 0.75 | CNR1 (0.41) | CNR1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL4755336 | 0.74 | LMNA (0.42) | ALDH1A1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL31412247 | 0.65 | ELANE (0.41) | ALDH1A1KMT2AMEN1FPR2GAA | |
| SCHEMBL4935850 | 0.63 | NPC1 (0.37) | CNR1ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL31195695 | 0.63 | ELANE (0.40) | ALDH1A1KMT2AMEN1LMNAKDM4E | |
| SCHEMBL4755352 | 0.63 | GAA (0.34) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL11495931 | 0.61 | CNR1 (0.46) | CNR1ALDH1A1KMT2AMEN1FPR2 | |
| Propionic Acid SCHEMBL27718906 | 0.60 | FFAR3 (0.56) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL4756125 | 0.59 | L3MBTL1 (0.34) | ALDH1A1KMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008006070-A2 | COMPOUNDS AND COMBINATIONS THEREOF FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF USE THEREOF | ROSKAMP RESEARCH LLC (US) | 2008-01-10 | — | — | WO | disclosed |
| EP-1858325-A2 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF IDENTIFYING THE COMPOUNDS | Roskamp Research LLC (US) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006074419-A2 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF IDENTIFYING THE COMPOUNDS | ROSKAMP RESEARCH LLC (US) | 2006-07-13 | — | — | WO | disclosed |