SCHEMBL4758299

SCHEMBL4758299

CCN1C(C)=C(C(=O)O)C(CC)(c2ccccc2)C(C(=O)O)=C1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.42
KMT2A Q03164 4/20 0.42
MEN1 O00255 2/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
TSHR P16473 1/20 0.41
APEX1 P27695 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP2C19 P33261 1/20 0.40
OPRM1 P35372 3/20 0.38
OPRD1 P41143 3/20 0.38
OPRK1 P41145 3/20 0.38
BACE1 P56817 1/20 0.37
BACE2 Q9Y5Z0 1/20 0.37
MITF O75030 2/20 0.37
HCAR3 P49019 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP9 P14780 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4758273 0.87 CNR1 (0.39) LMNAKMT2AMEN1PKMALDH1A1
SCHEMBL3392997 0.82 TDP1 (0.40) LMNAKMT2AMEN1TDP1ALDH1A1
SCHEMBL4755316 0.81 HCAR2 (0.36) LMNAKMT2AMEN1TSHRHCAR2
SCHEMBL11008245 0.80 LMNA (0.39) LMNAKMT2AMEN1CYP1A2POLB
SCHEMBL4755372 0.77 TSHR (0.39) LMNAKMT2AMEN1CYP1A2POLB
SCHEMBL4084609 0.76 PRNP (0.40) LMNAKMT2ACYP1A2TDP1PYGM
SCHEMBL5454280 0.72 CYP19A1 (0.44) LMNAKMT2AMEN1TSHRTDP1
SCHEMBL7429615 0.72 TDP1 (0.37) LMNAKMT2AMEN1CYP1A2TSHR
SCHEMBL2365028 0.66 TSHR (0.37) LMNAKMT2AMEN1CYP1A2TSHR
SCHEMBL11426802 0.62 LMNA (0.64) LMNAKMT2AMEN1CYP1A2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119819362-A Photocatalyst for efficiently catalyzing and synthesizing halogenated aromatic hydrocarbon as well as preparation method and application thereof 中国石油大学(华东) 2025-04-15 CN disclosed
WO-2008006070-A2 COMPOUNDS AND COMBINATIONS THEREOF FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF USE THEREOF ROSKAMP RESEARCH LLC (US) 2008-01-10 WO disclosed
EP-1858325-A2 COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF IDENTIFYING THE COMPOUNDS Roskamp Research LLC (US) 2007-11-28 EP disclosed
WO-2006074419-A2 COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF IDENTIFYING THE COMPOUNDS ROSKAMP RESEARCH LLC (US) 2006-07-13 WO disclosed