Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003044 | 0.85 | HDAC6 (0.47) | OPRM1OPRK1HDAC6HDAC1HDAC3 | |
| Hydrochloric Acid SCHEMBL4598799 | 0.84 | HDAC6 (0.46) | OPRM1OPRK1HDAC6HDAC1HDAC3 | |
| SCHEMBL4598564 | 0.82 | HDAC8 (0.55) | HDAC6HDAC1HDAC8 | |
| SCHEMBL5125952 | 0.81 | SLC1A3 (0.39) | HDAC6HDAC1CARM1PRMT6 | |
| SCHEMBL21628403 | 0.80 | OPRM1 (0.52) | OPRM1OPRK1HDAC6HDAC1HDAC3 | |
| SCHEMBL14003068 | 0.78 | OPRM1 (0.48) | OPRM1OPRK1HDAC6HDAC1HDAC3 | |
| SCHEMBL21628787 | 0.78 | OPRM1 (0.51) | OPRM1OPRK1HDAC6HDAC1PTGER4 | |
| SCHEMBL5129744 | 0.78 | MMP9 (0.38) | CARM1PRMT6 | |
| SCHEMBL5125574 | 0.78 | HDAC8 (0.49) | HDAC6HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL4596795 | 0.77 | OPRM1 (0.47) | OPRM1OPRK1HDAC6HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200521-A1 | Novel hydroxamic acid containing amino acid derivatives | BEXEL PHARMACEUTICALS. INC. | 2008-08-21 | — | — | US | claimed |
| EP-1906731-A2 | NOVEL HYDROXAMIC ACID-CONTAINING AMINO ACID DERIVATIVES | Bexel Pharmaceuticals Inc (US) | 2008-04-09 | — | — | EP | claimed |
| WO-2007005603-A2 | NOVEL HYDROXAMIC ACID-CONTAINING AMINO ACID DERIVATIVES | BEXEL PHARMACEUTICALS, INC. (US) | 2007-01-11 | — | — | WO | claimed |
| US-20070004776-A1 | Novel hydroxamic acid-containing amino acid derivatives | BEXEL PHARMACEUTICALS, INC. | 2007-01-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200521-A1 | Novel hydroxamic acid containing amino acid derivatives | HGFAC, HCAR2, BCAT1 | OPRM1 4437/4885OPRK1 3467/4885HDAC6 639/4885 |
| US-20070004776-A1 | Novel hydroxamic acid-containing amino acid derivatives | HGFAC, HCAR2, BCAT1 | OPRM1 4411/4885OPRK1 3401/4885HDAC6 684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.