SCHEMBL4758341 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	ALDH1A1	P00352	2/20	0.39

▸	PTP4A3	O75365	1/20	0.33

▸	TP53	P04637	2/20	0.33

▸	LMNA	P02545	1/20	0.33

▸	MAPT	P10636	1/20	0.33

▸	TDP1	Q9NUW8	2/20	0.32

▸	TRPA1	O75762	1/20	0.32

▸	HDAC8	Q9BY41	1/20	0.30

▸	TSHR	P16473	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2658682	0.80	PTP4A3 (0.46)	ALDH1A1PTP4A3TP53TDP1TRPA1
SCHEMBL28734149	0.76	NFE2L2 (0.41)	ALDH1A1TP53LMNAMAPTTDP1
SCHEMBL29603833	0.76	NFE2L2 (0.41)	ALDH1A1TP53LMNAMAPTTDP1
SCHEMBL29662132	0.73	NFE2L2 (0.50)	ALDH1A1TP53LMNAMAPTTDP1
SCHEMBL248639	0.73	NFE2L2 (0.50)	ALDH1A1TP53LMNAMAPTTDP1
SCHEMBL4758378	0.72	ALDH1A1 (0.34)	ALDH1A1TP53TDP1TRPA1
SCHEMBL95486	0.72	CES2 (0.43)	ALDH1A1TDP1
SCHEMBL11427991	0.71	MCL1 (0.35)	ALDH1A1TDP1TRPA1
SCHEMBL22869168	0.70	ALDH1A1 (0.46)	ALDH1A1TP53LMNAMAPTTDP1
SCHEMBL27613550	0.70	PTGDR2 (0.40)	ALDH1A1TP53TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009003009-A1	SUBSTITUTED PYRROLIDINE AS ANTI-INFECTIVES	ENANTA PHARMACEUTICALS, INC. (US)	2008-12-31	—	—	WO	disclosed