Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758386 | 0.84 | MEN1 (0.40) | MAOAMAPTALDH1A1KMT2ALMNA | |
| SCHEMBL4758781 | 0.83 | PKM (0.41) | ALDH1A1HCAR2LMNA | |
| SCHEMBL4757207 | 0.77 | GABRP (0.34) | — | |
| SCHEMBL29829123 | 0.75 | MAOA (0.50) | MAOAALDH1A1NPSR1HTTLMNA | |
| SCHEMBL28798831 | 0.75 | MAOA (0.50) | MAOAALDH1A1NPSR1HTTLMNA | |
| SCHEMBL4756681 | 0.72 | HSD17B10 (0.45) | MAPTALDH1A1HCAR2HSD17B3SLC6A19 | |
| SCHEMBL4756679 | 0.72 | HSD17B10 (0.45) | MAPTALDH1A1HCAR2HSD17B3SLC6A19 | |
| SCHEMBL1366060 | 0.71 | EPHX1 (0.59) | MAOAMAPTALDH1A1NPSR1KMT2A | |
| SCHEMBL31275816 | 0.70 | MAOA (0.55) | MAOAMAPTALDH1A1NPSR1MAOB | |
| SCHEMBL3093787 | 0.70 | MAOA (0.55) | MAOAMAPTALDH1A1NPSR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073534-A1 | METAL OXIDE AND SULFUR-CONTAINING COATING COMPOSITIONS, METHODS OF USE, AND ARTICLES PREPARED THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2008-06-19 | — | — | WO | disclosed |