Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.79 |
| ▸ | THRB | P10828 | 10/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.79 |
| ▸ | BLM | P54132 | 9/20 | 0.79 |
| ▸ | RECQL | P46063 | 8/20 | 0.79 |
| ▸ | MAPT | P10636 | 7/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.79 |
| ▸ | BRCA1 | P38398 | 6/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.79 |
| ▸ | USP2 | O75604 | 5/20 | 0.79 |
| ▸ | HTT | P42858 | 5/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.79 |
| ▸ | TOP2A | P11388 | 5/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.79 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.79 |
| ▸ | APEX1 | P27695 | 3/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zorubicin SCHEMBL28142133 | 0.97 | MEN1 (0.82) | MEN1THRBKMT2ABLMRECQL | |
| Zorubicin SCHEMBL8232 | 0.96 | S100A4 (0.84) | MEN1THRBKMT2ABLMRECQL | |
| Zorubicin SCHEMBL13840951 | 0.96 | S100A4 (0.84) | MEN1THRBKMT2ABLMRECQL | |
| Zorubicin SCHEMBL8231 | 0.96 | S100A4 (0.84) | MEN1THRBKMT2ABLMRECQL | |
| Zorubicin SCHEMBL1651187 | 0.96 | S100A4 (0.84) | MEN1THRBKMT2ABLMRECQL | |
| Zorubicin SCHEMBL29352324 | 0.96 | S100A4 (0.84) | MEN1THRBKMT2ABLMRECQL | |
| Zorubicin SCHEMBL29617182 | 0.95 | S100A4 (0.83) | MEN1THRBKMT2ABLMRECQL | |
| Zorubicin SCHEMBL4023 | 0.95 | S100A4 (0.83) | MEN1THRBKMT2ABLMRECQL | |
| Zorubicin SCHEMBL4024 | 0.95 | S100A4 (0.83) | MEN1THRBKMT2ABLMRECQL | |
| Zorubicin SCHEMBL27835878 | 0.94 | S100A4 (0.81) | MEN1THRBKMT2ABLMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080247987-A1 | Block Copolymer Compositions and Uses Thereof | ANGIOTECH INTERNATIONAL AG (CH) | 2008-10-09 | — | — | US | disclosed |
| US-20080124400-A1 | Microparticles With High Loadings Of A Bioactive Agent | ANGIOTECH INTERNATIONAL AG (CH) | 2008-05-29 | — | — | US | disclosed |
| EP-1909774-A2 | BLOCK COPOLYMER COMPOSITIONS AND USES THEREOF | ANGIOTECH INTERNATIONAL AG (CH) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007019439-A2 | BLOCK COPOLYMER COMPOSITIONS AND USES THEREOF | ANGIOTECH INTERNATIONAL AG (CH) | 2007-02-15 | — | — | WO | disclosed |
| US-20070026043-A1 | Medical devices combined with diblock copolymer compositions | ANGIOTECH INTERNATIONAL AG (CH) | 2007-02-01 | — | — | US | disclosed |
| CN-1878514-A | Soft tissue implants and anti-scarring agents | ANGIOTECH INT AG (CH) | 2006-12-13 | — | — | CN | disclosed |
| WO-2006002365-A2 | MICROPARTICLES WITH HIGH LOADINGS OF A BIOACTIVE AGENT | ANGIOTECH INTERNATIONAL AG (CH) | 2006-01-05 | — | — | WO | disclosed |
| WO-2005007129-A2 | TOPICAL FORMULATIONS WITH BIOACTIVE COMPONENTS | ANGIOTECH INTERNATIONAL AG (CH) | 2005-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080247987-A1 | Block Copolymer Compositions and Uses Thereof | ERBB3, LRBA, PPIB | MEN1 3461/4885THRB 1535/4885KMT2A 4666/4885 |
| US-20080124400-A1 | Microparticles With High Loadings Of A Bioactive Agent | FGF23, BMP2, BMP6 | MEN1 1184/4885THRB 4173/4885KMT2A 4676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.