SCHEMBL476034

SCHEMBL476034

CCC[Si](CCC)(CCC)OC(C)=O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.38
LMNA P02545 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PAOX Q6QHF9 1/20 0.32
TSHR P16473 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
FAAH O00519 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL704137 0.97 ALDH1A1 (0.36) ALDH1A1LMNAHSD17B10PAOXTSHR
SCHEMBL702862 0.93 ALDH1A1 (0.38) ALDH1A1LMNAHSD17B10PAOXFAAH
SCHEMBL704951 0.93 ALDH1A1 (0.38) ALDH1A1LMNAHSD17B10PAOXFAAH
SCHEMBL707205 0.90 ALDH1A1 (0.35) ALDH1A1LMNAHSD17B10PAOX
SCHEMBL475932 0.85 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10PAOXTSHR
SCHEMBL707669 0.83 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10PAOXTSHR
SCHEMBL706148 0.83 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10PAOXTSHR
SCHEMBL704795 0.83 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10PAOXTSHR
SCHEMBL475990 0.83 ALDH1A1 (0.43) ALDH1A1HSD17B10TSHRTDP1FAAH
SCHEMBL475993 0.81 FAAH (0.43) ALDH1A1HSD17B10TSHRTDP1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148446-B2 Silyl esters, their use in binder systems and paint compositions and a process of production thereof SIGMAKALON B.V. (NL) 2012-04-03 US claimed
US-20100249298-A1 Silyl esters, their use in binder systems and paint compositions and a process of production thereof GILLARD MICHEL 2010-09-30 US claimed
US-20070161722-A1 Silyl Esters, Their Use in Binder Systems and Paint Compositions and a Process for Production Thereof SIGMA COATINGS B.V. (NL) 2007-07-12 US claimed
EP-1620514-A2 SILYL ESTERS, THEIR USE IN BINDER SYSTEMS AND PAINT COMPOSITIONS AND A PROCESS OF PRODUCTION THEREOF SigmaKalon B.V. (NL) 2006-02-01 EP claimed
EP-1606329-A1 A PROCESS FOR THE PRODUCTION OF ACID GROUP CONTAINING POLYMER RESIN SigmaKalon B.V. (NL) 2005-12-21 EP claimed
US-20050222446-A1 Process for the production of hydrocarbyl silyl carboxylate compounds SIGMA COATINGS B.V. (NL) 2005-10-06 US claimed
EP-1572701-A1 PROCESS FOR THE PRODUCTION OF HYDROCARBYL SILYL CARBOXYLATE COMPOUNDS SIGMA COATINGS B.V. (NL) 2005-09-14 EP claimed
WO-2004099326-A2 SILYL ESTERS, THEIR USE IN BINDER SYSTEMS AND PAINT COMPOSITIONS AND A PROCESS OF PRODUCTION THEREOF SIGMAKALON B.V. (NL) 2004-11-18 WO claimed
EP-1475415-A1 Silyl esters, their use in binder systems and paint compositions and a process of production thereof SigmaKalon Services B.V. (NL) 2004-11-10 EP claimed
WO-2004085502-A1 A PROCESS FOR THE PRODUCTION OF ACID GROUP CONTAINING POLYMER RESIN SIGMAKALON B.V. (NL) 2004-10-07 WO claimed
EP-1462472-A1 A process for the protection of acid groups in polymers Sigma Kalon Services B.V. (NL) 2004-09-29 EP claimed
EP-1462467-A1 A process for the production of silyl group containing polymer resin Sigma Kalon Services B.V. (NL) 2004-09-29 EP claimed
WO-2004056837-A1 PROCESS FOR THE PRODUCTION OF HYDROCARBYL SILYL CARBOXYLATE COMPOUNDS SIGMA COATINGS B.V. (NL) 2004-07-08 WO claimed
US-3993839-A ORGANO-SILOXY TITANIC ACID ESTERS SHINETSU CHEMICAL COMPANY (JA) 1976-11-23 US claimed
US-12403437-B2 Method for producing nanodiamonds doped with group 14 element, and method for purifying same DAICEL CORPORATION (JP) 2025-09-02 US disclosed
US-12351463-B2 Heteroatom-doped nanodiamond DAICEL CORPORATION (JP) 2025-07-08 US disclosed
CN-113631252-B Method for producing and purifying nanodiamond doped with carbon group element 株式会社大赛璐 2025-05-23 CN disclosed
US-4640830-A VAPOR PHASE REACTION OF TRANSITION METAL, ORGANO-SILICON, AND CARBON COMPOUNDS NIKKISO CO., LTD. (JP) 1987-02-03 US disclosed
EP-0174622-A2 A process for preparing fine fibers NIKKISO CO., LTD. (JP) 1986-03-19 EP disclosed
US-3993839-A ORGANO-SILOXY TITANIC ACID ESTERS SHINETSU CHEMICAL COMPANY (JA) 1976-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249298-A1 Silyl esters, their use in binder systems and paint compositions and a process of production thereof LCT, PCMT1, TST ALDH1A1 2426/4885LMNA 3691/4885HSD17B10 1741/4885
US-20050222446-A1 Process for the production of hydrocarbyl silyl carboxylate compounds FTO, SUCLG2, ALKBH3 ALDH1A1 212/4885LMNA 3152/4885HSD17B10 374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.