Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 9/20 | 0.53 |
| ▸ | METAP2 | P50579 | 2/20 | 0.50 |
| ▸ | METAP1 | P53582 | 2/20 | 0.50 |
| ▸ | CBFB | Q13951 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | TCF4 | P15884 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720946 | 0.85 | CBFB (0.50) | AMY1ACBFBAURKAKDRNPC1 | |
| SCHEMBL2308847 | 0.84 | RAB9A (0.54) | AMY1AKDRNPC1ALDH1A1RAB9A | |
| SCHEMBL13658385 | 0.78 | AMY1A (0.57) | AMY1AMETAP2METAP1CBFBCYP11B1 | |
| SCHEMBL2315219 | 0.78 | AMY1A (0.57) | AMY1AMETAP2METAP1CBFBCYP11B1 | |
| SCHEMBL2309659 | 0.78 | PDE5A (0.55) | METAP2METAP1AURKAKDRNPC1 | |
| SCHEMBL4761477 | 0.78 | FGFR1 (0.57) | KDRNPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL2317512 | 0.76 | AMY1A (0.55) | AMY1AMETAP2METAP1CBFBCYP11B1 | |
| SCHEMBL2317508 | 0.76 | AMY1A (0.55) | AMY1AMETAP2METAP1CBFBCYP11B1 | |
| SCHEMBL12431145 | 0.75 | PDE5A (0.43) | METAP2METAP1AURKAKDRNPC1 | |
| SCHEMBL2314913 | 0.75 | AMY1A (0.51) | AMY1AMETAP2METAP1CBFBCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888579-A2 | NOVEL FLUORENE DERIVATIVES, COMPOSITION CONTAINING SAID DERIVATIVES AND THE USE THEREOF | Aventis Pharma S.A. (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006123061-A2 | FLUORENE DERIVATIVES, COMPOSITION CONTAINING SAID DERIVATIVES AND THE USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2006-11-23 | — | — | WO | disclosed |