Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 4/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 5/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570307 | 0.98 | ENPEP (0.36) | ENPEPMTNR1AMTNR1BALDH1A1TRPV1 | |
| SCHEMBL6569603 | 0.98 | ENPEP (0.36) | ENPEPMTNR1AMTNR1BALDH1A1TRPV1 | |
| SCHEMBL20149719 | 0.83 | PLA2G2C (0.45) | MTNR1AMTNR1BALDH1A1PLA2G2C | |
| SCHEMBL11693818 | 0.81 | TGFBR1 (0.44) | ENPEP | |
| SCHEMBL6570305 | 0.80 | MTNR1A (0.34) | ENPEPMTNR1AMTNR1BALDH1A1TRPV1 | |
| SCHEMBL6569599 | 0.80 | MTNR1A (0.34) | ENPEPMTNR1AMTNR1BALDH1A1TRPV1 | |
| SCHEMBL11860565 | 0.78 | MTNR1A (0.38) | MTNR1AMTNR1BALDH1A1ACACB | |
| SCHEMBL3210920 | 0.78 | ENPEP (0.33) | ENPEPALDH1A1TRPV1PLA2G2C | |
| SCHEMBL2335324 | 0.77 | TSHR (0.48) | ENPEPALDH1A1ACACB | |
| SCHEMBL16979552 | 0.77 | ENPEP (0.43) | ENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4156795-B2 | — | — | 2008-09-24 | — | — | JP | claimed |
| EP-1051393-B1 | NEW DERIVATIVES OF SULFONIC, PHOSPHONIC AND PHOSPHINIC AMINOALKANE ACIDS, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | MERCK SANTE SAS (FR) | 2003-10-01 | — | — | EP | claimed |
| JP-2002501040-A | — | — | 2002-01-15 | — | — | JP | claimed |
| EP-1051393-A1 | NEW DERIVATIVES OF SULFONIC, PHOSPHONIC AND PHOSPHINIC AMINOALKANE ACIDS, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | LIPHA (FR) | 2000-11-15 | — | — | EP | claimed |
| WO-1999037606-A1 | NEW DERIVATIVES OF SULFONIC, PHOSPHONIC AND PHOSPHINIC AMINOALKANE ACIDS, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | LIPHA (FR) | 1999-07-29 | — | — | WO | claimed |
| EP-1051393-B1 | NEW DERIVATIVES OF SULFONIC, PHOSPHONIC AND PHOSPHINIC AMINOALKANE ACIDS, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | MERCK SANTE SAS (FR) | 2003-10-01 | — | — | EP | disclosed |
| US-6265437-B1 | ALCOHOLISM | LIPHA (FR) | 2001-07-24 | — | — | US | disclosed |
| EP-1051393-A1 | NEW DERIVATIVES OF SULFONIC, PHOSPHONIC AND PHOSPHINIC AMINOALKANE ACIDS, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | LIPHA (FR) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037606-A1 | NEW DERIVATIVES OF SULFONIC, PHOSPHONIC AND PHOSPHINIC AMINOALKANE ACIDS, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | LIPHA (FR) | 1999-07-29 | — | — | WO | disclosed |